In fall 2003, Coheed and Cambria issued In Keeping Secrets of Silent Earth: 3. The vibrant sophomore effort (part three of the five-part saga) resulted in moderate success on the Billboard charts, with the singles "A Favor House Atlantic" and "Blood Red Summer" faring well on such media outlets as MTV. Coheed and Cambria subsequently toured North America with Thursday, Thrice, AFI, and Rainer Maria. They also joined the tenth annual Warped Tour in summer 2004 and embarked on their first headlining European tour, whose dates coincided with the success of the "Favor House Atlantic" single. The invigorated band then returned with Good Apollo I'm Burning Star IV, Vol. 1: From Fear Through the Eyes of Madness in September 2005; the album (part four) was also the first installment of a two-part conclusion to the band's running sci-fi story line. Released by Columbia, it hit number seven on Billboard's Top 200, partially due to the success of "The Suffering" and "Welcome Home."
All was not well within the group, however, and both bassist Michael Todd and drummer Josh Eppard departed in 2006. While the band paused to sort out its future, Equal Vision released the debut from Sanchez's indie electronic solo project, the Prize Fighter Inferno, that October. Entitled My Brother's Blood Machine, the album continued in the tradition of Sanchez's primary group, spinning a tale of three families in a story that predates the Coheed/Cambria saga and is narrated by Inferno (aka Jesse, Coheed's brother). Meanwhile, Sanchez and Stever decided to carry on and, bolstered by the return of Todd and the temporary enlistment of Foo Fighters drummer Taylor Hawkins, began recording their fourth album, Good Apollo I'm Burning Star IV, Vol. 2: No World for Tomorrow. The group's lineup was soon cemented with the addition of ex-Dillinger Escape Plan drummer Chris Pennie, and the album -- part two of the saga's two-tiered conclusion -- was released in October 2007, followed by the live recording Neverender: Children of the Fence in 2009. In 2010 the band returned with Year of the Black Rainbow, which served as a prequel to the Amory Wars story line. In the fall of 2012, Coheed and Cambria released the first of a two-part album, Afterman: Ascension. Its sequel, Afterman: Decension, appeared in February of 2013.