I believe this song has to do with people with consciences as their recollecting about the sins & bad choices (drugs, guns & hookers) they've made & realizing the weight of what they've done is so heavy. They did these terrible acts feeling like they had almost a god complex & now they have to walk around carrying the guilt from what they have done for the rest of their lives (like god carried the cross).
I believe this song has to do with people with consciences as their recollecting about the sins & bad choices (drugs, guns & hookers) they've made & realizing the weight of what they've done is so heavy. They did these terrible acts feeling like they had almost a god complex & now they have to walk around carrying the guilt from what they have done for the rest of their lives (like god carried the cross).