Lyric discussion by lbguitarist 

Cover art for 4:00 A.M. lyrics by Avenged Sevenfold

My guess, both from studying the lyrics and relating it to my own life, is that it's about the dangers of mental illnesses and how much they can control people's lives if sufferers aren't careful to monitoring the symptoms.

The first verse talks about overthinking the tiniest things and how it's probably nothing wrong at all yet an anxious person's mind will be racing a million miles an hour trying to understand what's going on.

The chorus focuses more as a make-or-break statement. It's basically a metaphor saying "if you don't break free of the shackles of anxiety/mental disorders, you'll simply permit them to control your life in the long run and miss out on so much in life".

Second verse focuses more on someone's realization that anxiety is taking over their life. Not really much more I can get from this verse to be honest.

The bridge talks about someone coming to the realization that their mental illness will cloud them forever, but they still have a life they can take control of and live to the best of their ability.

Not sure if this has any significance to the meaning of the song, but almost five years ago to the day, Zacky posted on the Avenged Sevenfold Twitter page: "Tracking is complete. There are no words that will ever describe the feeling of listening to this album while driving home alone at 4 am."

My Interpretation