Lyric discussion by wherestherealsky 

I agree. Its about drugs, but its also a love song about these two characters. I think the serotonin line refers to the girl he's chatting up, not the drugs. I think its about using drugs to maybe be someone else, going from this shy retirer to a more confident guy (I lost my social skills...) that decides he "wants to fall in love" and goes for it, chatting up this girl

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