Lyric discussion by Wilson3000 

Cover art for Blast Off lyrics by Frank Black and the Catholics

My immediate thoughts was he was referring to Thomas Becket who was killed at the "behest" of Henry II. When they examined the body they were astonished to find he was wearing lice-ridden underwear to display penance to God. Thusly, blasting off would make you feel as if bugs were crawling all over you.