Lyric discussion by PairOFish 

Maybe has to do with drugs. But the title "Big Nothing" much more likely refers to life itself.

"You can do what you want to whenever you want to" is optimistic sounding, but for the depressed nihilist, it loses its meaning. Life loses its meaning when you realize that even doing what you want won't add up to anything. All this work, all this hype over what you're going to do with your life, and in the end the reality is that it's rather pointless. Life is the Big Nothing. And I guess to combat this realization, people often turn to drugs to cope, which is where the drug references would tie in.

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