Lyric discussion by msefkhh 

Cover art for My Brain Hurts lyrics by Screeching Weasel

This sounds sounds like it's about not relating to other people and therefore not trusting them. Ultimately, feeling alien to everyone, whether or on TV, or to your significant other. And when realizing that, you realize you can't trust anyone to do anything correctly, and ultimately that you can't trust anything anyone says... And now you're left trying to put the pieces back together on your own.