Lyric discussion by artsyemma224 

Cover art for St Jude lyrics by Florence + the Machine

I've got a pretty bizarre theory about this song so bare with me. I think the song is written from the perspective of death and first realizing that when she touches people she kills them. St. Jude represents a miracle or good medicine or whatever that is saving the person. The song is written addressing the person close to death. This is my theory. It's pretty morbid but the lyrics tell the story for me. The song has a helpless tone (death having the loneliest existence) and well as an admiration of St. Jude.

My Interpretation