Lyric discussion by live101587 

Cover art for 10's lyrics by Pantera

10s is referring to the string gauge used for the guitars.

@live101587 I think it's a little deeper than that.

@live101587 The song is about Heroin, which comes through right on the opening line "My skin is cold, transfusion with somebody morose and old". If you listen to his speech at Layola college, he describes when he wakes up and his bones are freezing until he has his first fix of the day.

10s refers to bundles of heroin (1 bundle = 10 bags)

My Interpretation