Lyric discussion by aboyinastitch89 

Cover art for And It Spread lyrics by Avett Brothers, The

It just occurred to me that he could be talking about a different person in the first verse and the last. Like, "you" refers to the object of his affections, rather than one particular individual.

If "you" has "a brand new laugh and a different face," that suggests a new, or at least radically changed, person. I like that better too, so I'm gonna roll with it.

My Interpretation