Lyric discussion by CheckersMcGavern 

Cover art for Two Against One lyrics by Danger Mouse and Daniele Luppi

This is an absolutely fantastic song. And if you haven't seen the music video, I highly recommend it. The animation is incredible.

As for the song meaning... It definitely looks like it's about a man who is struggling with his 'inner demons', so to speak. However, I believe he is talking to someone who is attempting to help him. Perhaps a psychologist or just a caring friend.

"Make no mistake I don't do anything for free I keep my enemies closer than my mirror ever gets to me" He is telling this person that he is a cautious man. Un-trusting. Maybe even paranoid?

"Wait til you feel the warmth of my gratitude." Asking for help, or just accepting an offer of help.

"I get the feeling that it's two against one" Two real people fighting his mirror self/inner demon/problems.

"The mirror is a trigger and your mouth's a gun Lucky for me, I'm not the only one" Looking in the mirror must trigger his self hatred. He also thinks that the person who is helping him has the ability to end his struggle.

"And if it looks to me like you in your reflection Plan to add your own fight to this dimension Then tell it this ain't no free-for-all to see There's only three, it's just you and me against me" Basically, he doesn't want anyone else to help.

"And if your foot soldiers, sycophants, and yes-men Plan to break into the middle of this little plan Then there's your plan to hear me say That I won't play around the way Anyway, I plan to plan around them" This one is a bit fuzzy. Perhaps it means that... if this person does bring others in to help... that he'll pretend like nothing is wrong?

I interpreted that last stanza as hospital personnel "foot soldiers (Nurses), sycophants (Residents or Medical Students), yes men ( Consultants) & his planned suicide, how he was going to outsmart "them" by planning "around them" for a successful demise.