Lyric discussion by Manodeath 

Like flexible mentioned, I agree that the song is probably about suicide, however I get the imagery of a pilot no longer wanting to fly the plane, and is bracing himself for impact.

Lyrics like "Mayday, ground control to no one, Empty the seats and put away the maps", can be taken as no one cares whether the person does crash and burn, hence said individual decides to give up his responsibilities, and his life.

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