Lyric discussion by sawbones420 

Cover art for Tangled up in Plaid lyrics by Queens of the Stone Age

It's about their former bassist, Nick Oliveri. His exit from the band was based on personal reasons, and Josh was very broken up about having to kick him out as they'd been playing together since before Kyuss formed. The title is a reference to Nick's punk rock musical leanings.

Sorry I don't have a link, but I remember reading an interview with Josh where he said he was in a really dark place while they were writing/recording this album because of the falling out with Nick. He said that the mood of most of the songs reflected this. It doesn't seem surprising that one of the songs on the album addresses Nick's parting directly.

Song Meaning

I have to agree with this opinion. Some have mentioned a soured relationship & a self-destructive person. If you know why Oliveri was kicked out & the situation he got himself into post-QOTSA, it becomes crystal clear.