I think he's talking about a girl that left him for a total asshole. He's trying to forget her, but he can't. He remembers being with her when they were both on drugs, feeling paranoid. He tries to concentrate on work ("main man" might be a reference to his manager or a record company), but no matter what, something always reminds him. The "thick mud" is his struggle to move on to somebody new(new blood). Both of them are clean for the time being, and don't want to go back to where they were. Elliott sees that he's better off without her, but he still misses her.
I think he's talking about a girl that left him for a total asshole. He's trying to forget her, but he can't. He remembers being with her when they were both on drugs, feeling paranoid. He tries to concentrate on work ("main man" might be a reference to his manager or a record company), but no matter what, something always reminds him. The "thick mud" is his struggle to move on to somebody new(new blood). Both of them are clean for the time being, and don't want to go back to where they were. Elliott sees that he's better off without her, but he still misses her.