Lyric discussion by mentalmystic 

Cover art for 501 lyrics by Sequoyah Prep School

I think its driving drunk while pondering about his uneasy relationship.

"With a bottle between my thighs Im praying I see the city limits sign"

Feeling down and hoping not to get in a wreck while thinking about his girlfriend and their troubles. It indicates that there's a specific problem that she isn't ok with, perhaps the drinking.

"She says why do you do what you do I can't always come back to you I don't know why I do what I do But I'll always come back to you"

Overall its a really great song :]

My Interpretation