Back Against The Wall Lyrics

Lyric discussion by Rhcook 

Cover art for Back Against The Wall lyrics by Cage the Elephant

With the way the song sounds and all the lyrics in the first few lines mostly I think it's about drug abuse

I see that as well. The video adds a lot with him fidgeting around in bed and such. Probably a broader meaning to the song(someone mentioned sin in general), but you can easily make the drug abuse connection(speaking from experience).