This is what David said it was about in that EW interview with Chris Willman...
Was the title of "Mr. Sensitive" meant to be ironic in any way?
David: The song was unintentionally ironic. I had the harmonic riff in my head for five months. In my lyric journal, I had "Mr. Sincere" written down, and sincere turned into sensitive. I wanted to write about something outside myself and get a little metaphorical. He lives in a village devoid of feeling. They get so afraid of this child who has feelings that they kill him. It kind of took on this Tim Burton-like, twisted vision of James and the Giant Peach for me. But I know people look at me as that sensitive guy.
This is what David said it was about in that EW interview with Chris Willman...
Was the title of "Mr. Sensitive" meant to be ironic in any way?
David: The song was unintentionally ironic. I had the harmonic riff in my head for five months. In my lyric journal, I had "Mr. Sincere" written down, and sincere turned into sensitive. I wanted to write about something outside myself and get a little metaphorical. He lives in a village devoid of feeling. They get so afraid of this child who has feelings that they kill him. It kind of took on this Tim Burton-like, twisted vision of James and the Giant Peach for me. But I know people look at me as that sensitive guy.