I think he's talking about a friend who's unreliable and disappears on him all the time due to a big drug problem. He probably knew them from back in the day when he had a drug problem too so when they suddenly appear in his life again, it brings back all the skeletons in his closet.
"Seems it never ends, Double nickels on your dime" --Still buying drugs
"Theres a killer on the corner and he's looking for love" --Drug dealer looking for them
"And to tell you the truth i lost my faith in you" --He doesn't think they will beat the habit
"And these unspoken Lies appear at the worst times" --They deny it
I think he's talking about a friend who's unreliable and disappears on him all the time due to a big drug problem. He probably knew them from back in the day when he had a drug problem too so when they suddenly appear in his life again, it brings back all the skeletons in his closet.
"Seems it never ends, Double nickels on your dime" --Still buying drugs "Theres a killer on the corner and he's looking for love" --Drug dealer looking for them
"And to tell you the truth i lost my faith in you" --He doesn't think they will beat the habit
"And these unspoken Lies appear at the worst times" --They deny it
He basically wants them to disappear again