Lyric discussion by leftmysoulbythesea 

Cover art for Annie, Use Your Telescope lyrics by Jack's Mannequin

I'm not big on thinking every song of his is about the cancer, but this one sounded way too familiar. I worked in the Cancer field for a long time and I had so many patients (before they died) tell their family to look to the sky and the stars and they would be there.

I think it's about Andrew being scared of dying, or not knowing.