Lyric discussion by escape.the.fate 

Cover art for The Fly lyrics by Dave Matthews

yeah... i think the "never missed a note" line reffers to the Twinkle Twinkle Little Star part (like born_betrayer said ) but i think its cuz everyone thought he couldnt play the piano when he was playing the other notes during the song but his uncle knew what he was doing. His mom said something along the lines of "what the hell is he doing" and her brother (Josh's uncle) Ned replied "i think he is hitting every note". It shows how he is the only one who actually gets Josh. (i kno that more than likely doesn't make sense... but i never do so.... sorry)