Lyric discussion by GeneralDisorder 

Cover art for Human Wheels lyrics by John Mellencamp

I agree that this is a great song, and I'm surpirsed there are not more comments.

I think the song is written from the perspective of someone who is mourning the death of someone they loved and admired, possibly a "larger than life" father figure. This loss is causing him to reflect on the nature of life and death. He experiences a feeling of insignificace. There is also a recognition that life goes on (human wheels spin round and round) while our time on earth always grows shorter (while the clock keeps the pace).

The lyrics are full of images of death and burial ("draw its last breath" "vault" "pale reflection" and "dust to which this flesh shall return").