Lyric discussion by readmedotexe 

Cover art for In The Fade lyrics by Queens of the Stone Age

Although I haven't taken the time to analyze every detail, in a very general sense this is what "In the Fade" means to me:

In spite of all our attempts to hold on to life, we simply cannot. In spite of all our worrying over death, there is nothing we can do to prevent the inevitable.

The author realizes this, and instead of fighting it or denying such a stark reality, he embraces death as a friend--whenever it comes.

I think it's a beautiful sentiment. I actually find a triumphant sense of peace every time I hear him say:

"Ain't gonna worry...there's nothing to save, and I know...you live till you die"

That's all there is, my friends. We might as well come to terms with it and make the best of our days above ground.

This is how I take the song, as well. This interpretation is much deeper and more meaningful than some dude leaving a girl.