Lyric discussion by ZenWolf 

Cover art for Drilled a Wire Through My Cheek lyrics by Blue October

Here's my psycho-analytical summary... which will probably only make sense if you've experienced it personally or are close to a person that has a personality disorder:

Often, clinically depressed people, especially those with personality disorders (Bipolar, Borderline, etc...) push everyone that cares about them out of their lives as they isolate themselves. [Possibly like Justin?]

However! Many will hold on to one person (usually a lover) that they view as their salvation. That they DESPERATELY try to keep, protect and show their love to. But they are in so much internal pain they usually only end up smothering and desperately controlling them (so they won't lose them)... and subsequently just end up hurting that person unintentionally.

Which starts a viciously painful cycle: The more they hurt that person, the more desperate they become to show that person how much they love them so they won't lose them and be alone... and the cycle starts to repeat.

Very similiar to abusive relationships where the abuser (after having abused the other person) will become the nicest, most loving, sincere, apologetic person to keep the abused from leaving them. Staring a cycle of abuse.

It's all about the author being in pain and recognizing the Dr Jekyl/Mr Hyde aspect of the cycle and blaming himself for hurting her...

I would bet this song relates to "Hate Me" when later he finally leaves her to stop hurting her.