Lyric discussion by Safehome 

Cover art for Desperate Times lyrics by Killswitch Engage

It sounds like he is just talking about how when you at your lowest point and you feel like there is no point in continuing with anything, at all, look to Jesus for help.

The song always strikes me like he's talking about a man that is on the edge, and when he finally gets to his breaking point, where he would kill himself he has an epiphany.