The song was originally called "Cindy Lou", and was named for Buddy's niece, the daughter of his sister Pat Holley Kaiter. The title was later changed to "Peggy Sue" in reference to Crickets drummer Jerry Allison's girlfriend (and future wife), Peggy Sue Gerron, with whom he had recently had a temporary breakup.
The song was originally called "Cindy Lou", and was named for Buddy's niece, the daughter of his sister Pat Holley Kaiter. The title was later changed to "Peggy Sue" in reference to Crickets drummer Jerry Allison's girlfriend (and future wife), Peggy Sue Gerron, with whom he had recently had a temporary breakup.