Lyric discussion by I Am Jack! 

Cover art for What I Saw lyrics by John Frusciante

"And the pain of knowing you should have tried"

makes me think that it's to do with doing what you can before you run out of time, and try to do anything no matter how hard it is.

"Give me your hands And we'll never die"

I'm pretty sure that's just to do with teamwork, if you work together you can accomplish anything (like never dying?)