Lyric discussion by jetercp 

Cover art for Devil Running lyrics by John Butler Trio

i'm pretty sure i'm way off, but i see this as a anti-bush protest song. now, understanding completely that jbt are from australia, i do know they are very aware of the problems here in the united states as well.
but as for the song, it talks about an uneducated man, business falling apart and hand on the button of disaster - all of which relating to bush. so i see it as "i see the devil and the devil is running" - as in running our country. just my two cents.