Lyric discussion by basser 

Good lord. This song is permanently stuck in my head as a conversation from Wilson to House in "House, M.D."

Especially from the first few episodes of the third season where Wilson and Cuddy conspire to humble House, telling him is diagnosis was wrong when it wasn't... The whole song just sounds like Wilson trying to convince House he got the wrong treatment. "Don't you think that, possibly, this time, it's different? Don't you think that, maybe, this time, you were wrong?"

And the "I'm not trying to prove/say anything at all here" as Wilson's trying to soften the blow. I think he said something along the lines of "It doesn't hurt to be wrong sometimes, you're still a great doctor." while House rages that his diagnosis couldn't have possibly been wrong...

OH AND (I'm just getting on a roll here sorry) "Having spent your entire life Exactly where you are tonight In the valley between intent and deed" House attempts suicide about halfway through season 3, but fails and is left half-conscious on his floor by Wilson. Also there are several other instances where it seems like he can't muster the will to turn his intentions into actions. (Or vice-versa where his actions have nothing to do with good or sound intention.) PERFECT FIT #1.

And then... "You must have mastered this The fragile art of a good excuse The little things that get you to believe that get you to believe" House is always making excuses for his actions, 'the ends justify the means' kind of things. The "detox" episode shows how he constantly uses his damaged leg as an excuse for his vicodin addiction, trying to get himself to believe that his entire life was ruined by the injury and none of his misery can possibly be his own fault. This of course leads Wilson to say "And everything's the leg? Nothing's the pills?" to which House scoffs. .... PERFECT FIT #2.

Lastly: "You’ve spent your entire life Quick-tounged, and always right Hasn’t being right just let you down? right just left you down" And of course this one's easy. House, the master of sarcasm and wit, has indeed spent his life quick-tongued and always right, (which is actually why Cuddy and Wilson want to humble him with a 'wrong' diagnosis in the first place, House is starting to think he's god.) And the "right just lets/left you down" line always seemed to me to be all the instances of House preaching about human nature, how "everybody lies" and nobody ever does anything selflessly; and he's usually right, which just leaves him angrier and more miserable than before. Which means this is... PERFECT FIT #3

And that is why I get the urge to break out the House DVDs every time I hear this great song... And yes, I know. I'm total nerd. ;)

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