Bitter Pill Lyrics

Lyric discussion by Three23 

Cover art for Bitter Pill lyrics by Mötley Crüe

Vicodin, it's the bitter pill if you've ever let one sit on your tongue. She is addicting and will medicate your brain if you abused her intended use as a short-term pain killer, especially chased with alcohol.

No the term 'bitter pill' is not meant in the literal sense. It is a well known metaphor, usually said in the sentence such as 'it's a bitter pill to swallow'. Especially since their drugs of choice were coke and heroin and not vicodin. I think it's about addiction, specifically how no matter how hard you try it breaks your will and you do whatever it takes to score.