Lyric discussion by ibanezfender63 

Cover art for Turnin' On The Screw lyrics by Queens of the Stone Age

This is the best song on the album. I bought it yesterday, and I'v listened to this song at least 22 times.

I think it's about feeling awkward/not fitting in compared to the rest of society. Especially because of the Silence of the Lambs reference, and lines such as "The world is round, My square don’t fit at all" (My favorite line of the song). "Turning on the Screw" could mean going against what fits and what makes sense in society. The screw is conformity, and turning on it is rebellion.

The title reminds on of "Taming of the Shrew." Anyone else think of this?

The world is round, My square don’t fit at all