My take is that Bono is explaining the feeling of limbo, listlessness, and being lost after an emotional or physical strain (e.g. major accident, break-up, decision to move). Kind of like the post-traumatic stress one feels and trying to explain it to someone who wasn't affected. However, specifically, Bono does seem to single out interpersonal relationships explicitly.
My take is that Bono is explaining the feeling of limbo, listlessness, and being lost after an emotional or physical strain (e.g. major accident, break-up, decision to move). Kind of like the post-traumatic stress one feels and trying to explain it to someone who wasn't affected. However, specifically, Bono does seem to single out interpersonal relationships explicitly.
Peace