Lyric discussion by lizzieluvs2play 

Cover art for First Orgasm lyrics by Dresden Dolls, The

I think this song is actually a direct reference to masturbating, unlike most of the other songs that sound "dirty", but there is a very pronounced tone of lonliness in it too. She has decided to live without friends or lovers because she is too busy for them. She tries to "take matters into her own hands" but she's not happy about doing it. In the last lines she is actually begging for company. It's very sad...