Tears In A Vial Lyrics

Lyric discussion by TCLe 

Cover art for Tears In A Vial lyrics by Megadeth

Personally, I think this is talking about how he had to pass on a relationship in order to do something he really wanted to do. And decided that he'd do that and save his tears everytime he missed her. Which could mean thinking of the memories that he has kept in his mind.

The problem is that after he comes back to her, she's died of something and regrets ever leaving her side and missing her.