Lyric discussion by Blue_Man 

Cover art for Anaconda lyrics by Sisters of Mercy, The

Love this song. I've always seen it as being about heroin abuse, the anaconda being addiction slowly crushing the life out of the addict ("See her face turn to a mask, and passion turn to she-don't-care").

I love the vaguely snake-charmer-y sound to the guitars, as well. Groovy.