Lyric discussion by danya145 

Cover art for Poison lyrics by Alice Cooper

i don't think this song is about AIDS... it's simply about love that is not possible, or forbidden, or he just thinks that being romantically related to this person would eventually hurt him. that's all. "I hear you calling and it's needles and pins (And pins) I want to hurt you just to hear you screaming my name" "My pain, your thrill" maybe it has something to do with s&m?