Lyric discussion by DropsofRaine 

Cover art for Blister lyrics by Our Lady Peace

To me this song is about someone who is mentally disturbed. Lately I can't breathe Waiting, they're chasing me No one listens but I'm ok with it

I think this means something like his disturbed thoughts are chasing him, and he trys to get help, but no one belives him.

What if I was scared I'm waiting for... They're at my door But I'll be back again... The people at the door are psychitrists who came to take him away to get help.

You wonder why I don't know You shout at me let me go

This seams like people see him so sick, and they wonder why, but he cant explain it

It ends optimistically because of the line "i'll be back again" He's gone to get help, and he knows he'll come back better.