The Medication Is Wearing Off Lyrics

Lyric discussion by Llew66 

Cover art for The Medication Is Wearing Off lyrics by Eels

I think the song is actually about his mother. Both she and E's sister passed away when E started writing this album. The only reason I say it's about his mother and not his sister is the line "break your mothers heart". Also, E's sister was a huge part of how he got into music, so I would think he would use some type of musical object as a gift from her.