Lyric discussion by oball 

The boy in the bubble refers to those children with Severe Combined Immune Deficiency (SCID) who have to live in sterile environments because they lack the ability to fight off disease. The original "boy in the bubble" was referred to only as "David" and died in 1984 following an unsusccesful bone marrow transplant.

The baby with the baboon heart refers to a case in 1984 when a baby (Fae) who was born with hypoplastic left-heart syndrome, which is a lethal underdevelopment of the left side of the heart. In an effort to save her life, surgeons transplanted a heart from a baboon into her. It initially looked like it had worked, but baby Fae ultimately died.

I'd say these are invoked in the song as instances where technological advances keep alive people who would have died at birth without modern medicine - hence "These are the days of miracle and wonder".

Oball is correct. Incidentally, and significantly, the baby with the baboon heart was killed by a creationist. Yes, dramatic effect..."doomed" would be more accurate. The doctor who implanted the heart chose a baboon heart without regard to medical compatibility because he didn't believe humans and baboons are related. Consequently she died earlier than she might have with a more compatible heart (see

Does anyone (else) see a connection between the lyrics of Paul Simon's "The Boy in the Bubble" and Arthur C Clarke's short story "The Star"? Specifically, "... the way we look to a distant constellation that is dying in a corner of the sky ..."

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