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Iron & Wine – Prison on Route 41 Lyrics 11 years ago
I think the last verse of this song is pretty clear:

By the precepts of her purity
So unlike the habits of my whole family
Whom I only see down on my knees
In prayer by Virginia whom I live for to please

In this song, Virginia is the Virgin Mary, the protagonist's savior whose immaculate conception made her pure. He prays to her for guidance on his knees, and owes his life (out of prison, and in an ethereal sense) to her.

It's almost a Christmas song.

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