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30 Seconds to Mars – L490 (Equinox) Lyrics 12 years ago
There's an interpretation going around in the Echelon community about the connection to the painkiller (I've only read it on a Russian page with the help of Google translate and that is literally all I've seen of it, so I don't know how legit this is)

Apparently, Jared was suffering under major back pains and other health issues and the medication he used was L490. So, the song is sort of a lullaby from Shannon to Jared (presumably written to either ease his pain or maybe what he was feeling seeing his brother suffering translated into music?).

Reasons why I think this theory may not be completely false:
Jared is a perfectionist, idealist etc so everything on the albums must sound good, fit (City of Angels for example was written before TIW was released, yet it didn't make the album), be personal etc - they have to have a reason to be there. Although L490 is definitely experimental and sounds fine, it doesn't really fit the overall sound of the album (all of the other tracks sound like war songs, very powerful, very present; L490 is calm and actually does kinda sound like a lullaby). Not only is it on the album, during TIW tour, the played it very often live (yeah maybe to give Jared time to run to the other side for The Kill, but still - it wouldn't have 'just been there'). Also, I think it was the VyRT commentary about Artifact and then there's L490 playing when they're talking about Shannon and Jared said something like 'what's the song?', someone replied 'L490' and Jared goes something like 'oh of course, how could I forget that'. (there have been more mentions to the track, but this is the only one I can pinpoint).
So, my guess is that the song is personal and intimate for the two of them, which vouches for the theory that it is somehow connected to the medication and his pains.

my two cents. hopefully someone will ask them that in an interview and i can find out whether this was close.

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