Lyric discussion by JethroFloyd 

I always thought this song was a description of someone who is no longer mentally sound but still has to play with the band. A doctor is brought to see him and injects medicine just to keep him going, so he can get through one more show. The term "Comfortably Numb" also resonates deeply with me as the gradual numbing that begins when we first realise how morally depraved society and the human race in general are. "Comfortably Numb" is an easier state to inhabit than the constant awareness that we are living,sometimes, in a form of hell.

...which is pretty much the context it's used in for the movie. :)

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