Lyric discussion by TiredoftheShadowin 

Cover art for Winter Song lyrics by Screaming Trees

Sounds to me like it's about a risky lifestyle. Around that time, every day Mark "rolls the dice" with his lifestyle of scoring and taking drugs. The mention of jesus knocking on his door for the last time obviously implies death. It's not a reach to suggest his death, over a decade after he stopped using drugs, was likely influenced by his poor lifestyle. RIP.

My Interpretation