Lyric discussion by PraiseRa 

Cover art for Ghost of Perdition lyrics by Opeth

"Ghost of perdition Stuck in her chest"

Could figure it to be a possesion of Satan or just a simple fact that she has accepted Satan into her life

"A warning no one read"

Probably meaning she hid this pact from other, perhaps even acted Christian

"Road into the dark unaware Winding ever higher"

Like a downward spiral into the clutches of Satan

"In time the hissing of her sanity Faded out her voice and soiled her name"

Drove the mother insane over time

"To see a beloved son In despair of what's to come"

The son, knowing his mother is going mad, knows of whats soon to come(death)