Lyric discussion by obsequiousleaf 

Just a guess, but I think "sanding numbers off the monojects" refers to re-using needles so many times that the ink marking the quantity of liquid in the syringe gets rubbed off. Also, I'm guessing "slight returns" refers to tolerance and not a diminishing supply.

(I used to give liquid medication to my rabbit and I would wash and re-use the same (oral) syringe. The numbers rubbed off pretty quickly.)

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