Lyric discussion by VikingCustom 

this one ain't all that hard... prying open my third eye. that phrase is heavily emphasized in the song. assuming you understand the third eye reference and that the song has obvious references to both lsd and mescaline, try looking at the song as being less about the drugs and more about the rather unpleasant image of someone trying to pry their own eyes open with the drugs being the crowbar. hope someone finds this useful. peace.

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